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Director, Oncology Translational Medicine

Company: Job Juncture
Location: New Brunswick
Posted on: September 14, 2019

Job Description:

My client is expanding and looking to hire a Director of Oncology Translational Medicine. The ideal candidate will take on the following tasks:


  • Develop and implement translational science strategies supporting oncology projects in early to late stages of drug development
  • Plan and implement translational research including investigation of mechanism of action, mechanism of resistance, pharmacodynamics markers of target engagement, markers predictive of or correlating with clinical efficacy, and disease biology, in cooperation with preclinical research, biomarker group, clinical pharmacology and clinical development teams
  • Oversee the development and monitor the quality of pk/pd, pharmacogenomic and patient stratification biomarker assays to support the advancement of preclinical programs into the clinic
  • Build and maintain strong relationships and collaborations with key scientific and medical experts to incorporate external insights and maximize the generation of scientifically robust data to accelerate our drug development programs
  • Work with pre-clinical research teams to initiate the translational strategy planning of pre-clinical assets to establish the assays in support of the clinical program
  • Identify, develop and implement innovative analytical methods to address biomarker needs

    The ideal candidate will possess the following qualities:


    • PhD/MD with 8+ years experience, including 5+ years in developing biomarkers and translational medicine strategies during oncology drug development
    • 5+ years experience of applied translational science activities for clinical assets, including validation of biomarkers and patient selection assays for incorporation into multisite clinical trials
    • Knowledge of biomarker development and implementation in early stage oncology drug development to support clinical assay development and validation for mechanism of action, proof of biologic activity, proof of concept, patient stratification and response prediction markers
    • Experience with the development of companion diagnostics is a plus
    • Solid scientific understanding of the complexities and recent developments in the oncology field
    • Strong interpersonal skills and demonstrated ability to establishing effective collaborative relationships with internal stakeholders and external parties to ensure execution excellence
    • Exceptional oral, written and presentations communications skills

Keywords: Job Juncture, New Brunswick , Director, Oncology Translational Medicine, Executive , New Brunswick, New Jersey

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