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Senior Research Investigator - Engineering Technologies, Drug Product

Company: Bristol-Myers Squibb Company
Location: New Brunswick
Posted on: April 10, 2019

Job Description:

Bristol-Myers Squibb is seeking scientists/engineers to join the Engineering Technologies group within the Drug Product Science and Technology department. This role will be responsible for supporting the development of new small molecule and biological drug products via the development and application of enabling technologies. The successful candidate will collaborate with scientists across product development and manufacturing leveraging a combination of process analytical technologies, engineering fundamentals, and formulation sciences to aid in product design, process development and technology transfer. The successful candidate has a strong understanding of process analytics, analytical method development, engineering fundamentals, pharmaceutical science, and strong collaboration and communication skills. The individual works well with people from other disciplines and thrives in a multifunctional team environment. The successful candidate has expertise in one or more of the following areas: Process analytical technologies (PAT), analytical instrumentation, chemometrics, process modeling, formulation development, unit operation design, scale-up and technology transfer.Responsibilities:

  • Develop innovative process analytical tools (PAT) that provide drug product formulation and process understanding. Use Raman, IR, FT-Near Infrared, Particle sizing and other in-process type technologies to address the risk analysis of the process or product and implement controls to enhance robustness. These methods can encompass on-line and off-line.
  • Collaborate with commercial manufacturing teams to troubleshoot or enhance existing PAT methods use for commercial product manufacturing.
  • Accountable for providing innovative solutions and analyses which provide key insights and process knowledge for development, including scale-up and process optimization studies for projects within the portfolio.
  • Facilitate problem solving using scientific, engineering, and analytical techniques to support drug product development from early development to product launch as a member of a multidisciplinary project team.
  • Responsible for willingly and enthusiastically working in the laboratory to solve challenging pharmaceutical development problems using his/her expertise.
  • Responsible for actively collaborating with other key scientists within the team. Expected to consistently display a can-do attitude and demonstrate the willingness and capability to adapt and grow within a complex and changing environment.
  • Manage data, and metadata lifecycles from generation to knowledge, identifying opportunity to maximize the knowledge generated from the tools we have.Qualifications/Requirements:
    • Ph.D. in chemical or biomedical engineering, pharmaceutical science or analytical chemistry with 3-5 years of pharmaceutical industry experience.
    • M.S. in chemical or biomedical engineering, pharmaceutical science or analytical chemistry with 5-7 years of pharmaceutical industry experience.
    • B.S. in chemical or biomedical engineering, or chemistry with more than 7 years of pharmaceutical industry experience.
    • Excellent interpersonal, collaborative, team-building, and communication skills to ensure effective collaborations within matrix teams.

Keywords: Bristol-Myers Squibb Company, New Brunswick , Senior Research Investigator - Engineering Technologies, Drug Product, IT / Software / Systems , New Brunswick, New Jersey

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