Principal Scientist, Impurity Center of Excellence

Company: Bristol Myers Squibb
Location: New Brunswick
Posted on: June 25, 2022

Job Description:

At Bristol Myers Squibb, we are inspired by a single vision - transforming patients' lives through science. In oncology, hematology, immunology and cardiovascular disease - and one of the most diverse and promising pipelines in the industry - each of our passionate colleagues contribute to innovations that drive meaningful change. We bring a human touch to every treatment we pioneer. Join us and make a difference.Bristol Myers Squibb is recruiting for a Principal Scientist that is a key leadership position responsible for method development and characterization in biologics impurity center of excellence. The Impurity Center of Excellence is accountable for establishing analytical control strategy of biologics process related impurities including development of phase-appropriate analytical methods for drug candidates in Bristol Myers Squibb portfolio spanning early- and late-stage clinical programs through commercialization. This position reports to the head of Impurity CoE and serves as a key member in the CoE leadership team.The Principal Scientist will assist in formulating analytical strategy and decisions for the implementation of robust analytical techniques for the measurement and/or identification of impurities in biologic products. The Principal Scientist will be responsible for method development; the methods will be designed, developed, and optimized to identify, and quantitate residual process impurities in drug substance, including Host Cell Proteins.The Principal Scientist is expected have a demonstrated history of technical accomplishments, scientific critical thinking, and interpersonal and communication skills, both written and oral. The Principal Scientist will provide guidance to the direct reports (scientists) and other scientists in the CoE for method development and analytical control strategy and is expected to author and review scientific documents.Bristol Myers Squibb has a strong biologics portfolio of innovative therapeutics that includes approved biologic medicines and clinical assets in diverse compound modalities including bispecific, antibody, fusion protein, antibody-drug conjugate, and fixed dose combination regimes. The Principal Scientist will be working on multiple early-, mid-, and late-phase biologic compounds across various therapeutic modalities, and actively partner with various development & commercialization groups.Qualifications

• Ph.D. in biochemistry, pharmaceutical sciences, analytical chemistry, or a related discipline with 5-10 years of relevant experience in bio/pharmaceutical industry or M.S. with a minimum of 10-15 years of experience.
• Proficient with a variety of analytical techniques, such as LC-MS of host cell proteins or therapeutic proteins, immunoassays (ELISA), quantitative PCR (qPCR, ddPCR), HPLC, electrophoresis and related techniques.
• Working knowledge and hands on experience in developing robust analytical methods.
• Be able to work in a team environment, operate independently in alignment with departmental strategy, foster collaborations, and drive project and team deliverables.Bristol Myers Squibb is a global biopharmaceutical company whose mission is to discover, develop, and deliver innovative medicines that help patients prevail over serious diseases. One shared journey is moving us forward at Bristol Myers Squibb. Around the world, we are passionate about making an impact on the lives of patients with serious disease. We are empowered to apply our individual talents and ideas so that we can learn and grow together. We are driven to make a difference, from innovative research to hands-on community support. Bristol Myers Squibb recognizes the importance of balance and flexibility in our work environment. We offer a wide variety of competitive benefits, services, and programs that provide our employees with the resources to pursue their goals, both at work and in their personal lives.Around the world, we are passionate about making an impact on the lives of patients with serious diseases. Empowered to apply our individual talents and diverse perspectives in an inclusive culture, our shared values of passion, innovation, urgency, accountability, inclusion and integrity bring out the highest potential of each of our colleagues.Bristol Myers Squibb recognizes the importance of balance and flexibility in our work environment. We offer a wide variety of competitive benefits, services and programs that provide our employees with the resources to pursue their goals, both at work and in their personal lives.Physical presence at the BMS worksite or physical presence in the field is an essential job function of this role which the Company deems critical to collaboration, innovation, productivity, employee well-being and engagement, and enhances the Company culture.To protect the safety of our workforce, customers, patients and communities, the policy of the Company requires all employees and workers in the U.S. and Puerto Rico to be fully vaccinated against COVID-19, unless they have received an exception based on an approved request for a medical or religious reasonable accommodation. Therefore, all BMS applicants seeking a role located in the U.S. and Puerto Rico must confirm that they have already received or are willing to receive the full COVID-19 vaccination by their start date as a qualification of the role and condition of employment. This requirement is subject to state and local law restrictions and may not be applicable to employees working in certain jurisdictions such as Montana. This requirement is also subject to discussions with collective bargaining representatives in the U.S.Our company is committed to ensuring that people with disabilities can excel through a transparent recruitment process, reasonable workplace adjustments and ongoing support in their roles. Applicants can request an approval of accommodation prior to accepting a job offer. If you require reasonable accommodation in completing this application or if you are applying to a role based in the U.S. or Puerto Rico and you believe that you are unable to receive a COVID-19 vaccine due to a medical condition or sincerely held religious belief, during or any part of the recruitment process, please direct your inquiries to adastaffingsupport@bms.com. Visit careers.bms.com/eeo-accessibility to access our complete Equal Employment Opportunity statement.Any data processed in connection with role applications will be treated in accordance with applicable data privacy policies and regulations.

Keywords: Bristol Myers Squibb, New Brunswick , Principal Scientist, Impurity Center of Excellence, Other , New Brunswick, New Jersey