Scientist - Radioligand Binding Assays

Company: Freyr Solutions, Client: Global Pharma company
Location: Rahway
Posted on: May 18, 2025

Job Description:

Position: Scientist - Radioligand Binding Assays

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Location: Rahway, NJ 07065
Type: Onsite - Laboratory-Based - Contract Position

Overview:
We are hiring a Scientist to support Merck's Early Drug Discovery Team within the Mass Spectrometry & Biophysics group in Rahway, NJ. This is a hands-on, lab-based role involving radioligand binding assays, tissue culture, and data analysis as part of a high-impact discovery environment.

Qualifications:

B.Sc. with 6+ years, M.Sc. with 4+ years, or Ph.D. with 3+ years of relevant lab experience



Must-Have Skills:

Prior experience or willingness to perform radioligand binding assays (125I, 3H, 35S)


Tissue culture (cell plating, stimulation, harvesting)


Experience working with 96- and 384-well plates


Membrane preparation and data analysis using dose-response fitting



Preferred Skills:

Liquid handling automation (Echo, Bravo)


Plate readers (SpectraMax, EnVision)


ActivityBase or similar assay/data systems


Traditional or automated Western blotting techniques



Software Requirements:

Proficient in MS Office and Adobe PDF


GraphPad Prism, ActivityBase, ELNs (preferred but not required)



Key Responsibilities:

Execute radioligand binding assays and tissue culture-based binding protocols


Analyze and export data, generate reports, and document all work in ELN


Collaborate cross-functionally and contribute to assay development and optimization



This is a fast-paced, innovation-driven environment, and a great opportunity to work on cutting-edge drug discovery projects.

Keywords: Freyr Solutions, Client: Global Pharma company, New Brunswick , Scientist - Radioligand Binding Assays, Other , Rahway, New Jersey